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Jean-Claude Klein
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Curriculum Vitae
I was born in 1942 in Thionville
I received a PhD in electronics at the University of Nancy
I in 1975
Since 1969 I have been working at the Centre de Morphologie
Mathematique (CMM) of the Ecole
des Mines de Paris where I have been in charge of research groups devoted to:
- The design of dedicated Hardware Architectures
applied to real-time image processing
- The design of a Continuous Blood Glucose
Monitoring System
- Automatic eye fundus
image processing. This application is still in progress

Research Areas
Automatic Eye Fundus Image Processing
For more than 10 years, I
have been managing research about the processing of eye fundus
images, applied to Diabetic Retinopathy. This pathology is the main reason for
defective eyesight and blindness for under 55-year old
people, in industrial countries. The target of this research is the automatic
detection of Diabetic Retinopathy at its early stages, and the automatic
diagnosis and monitoring of this disease.
This is obtained by automatic detection and quantization of microaneurysms,
haemorrhages and exudates.
Our research and publications on this matter are available on the following
websites, which are both those of my PhD students:
Frédéric
Zana’s personal page dealing with the processing of
angiographic images
Thomas Walter’s personal page dealing with more recent research
about eye fundus color
images
General Hardware architectures
My group has designed numerous processors to implement the algorithms
proposed by the Mathematical Morphology. For example:

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ASIC PIMM1
40 000 gates - 1.5 µm
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FPGA-based
Processor Board
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Multimedia Hardware Architectures
This group is involved in different multimedia projects whose goals are
to design parallel hardware architectures to allow real-time image segmentation
in the framework of MPEG4 applications. For example:
- Momusys European program. In this program, the
objective is to propose an efficient parallelized implementation of the
Mathematical Morphological operators into DSP
- M4M
(MPEG FO(U)R MOBILES) which is part of the Medea European program. In this project, we will
participate to the design of ASICs which will be
dedicated to MPEG4 applications
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Continuous blood glucose monitoring system
Three laboratories are working on this project :
- Pr. G. Wilson, University
of Kansas, Department of
Chemistry, Lawrence, KS 66045,
USA
- Pr. G.
Reach, INSERM U.341, Paris,
France
- Dr.
J-C. Klein, ENSMP CMM, Paris,
France
The goal is to design a miniaturized system able to continuously display
the blood glucose level and to trigger an alarm in case of hypoglycemia. This
would be a major help for diabetic patients.
The system is composed of a :
- Miniaturized
bio-chemical sensor : diameter = 0.3 mm
- Electronic
Control Unit (ECU) in charge of processing the data provided by the
sensor, of storing and displaying the blood glucose value. The ECU can
also be used to transfer the stored data to a personal computer

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Electronic Control Unit
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Sensor implanted in the user's forearm
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The Electronic Control Unit is connected by wire to the sensor
This
program is currently funded by :
- The NIH : DK30718-11
- National
Applied Science, Portland, Oregon U.S.A.
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Address
Ecole des Mines
de Paris
Centre de Morphologie Mathematique
35, rue St-Honoré
77305 Fontainebleau
FRANCE
E-mail : klein@cmm.ensmp.fr
Phone : +33 1 64
69 47 06
Fax : +33 1 64 69 47 07
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Last modification : 28/03/2006