Jean-Claude Klein

 

Curriculum Vitae

I was born in 1942 in Thionville

I received a PhD in electronics at the University of Nancy I in 1975

Since 1969 I have been working at the Centre de Morphologie Mathematique (CMM) of the Ecole des Mines de Paris where I have been in charge of research groups devoted to:

  • The design of dedicated Hardware Architectures applied to real-time image processing
  • The design of a Continuous Blood Glucose Monitoring System
  • Automatic eye fundus image processing. This application is still in progress

Research Areas

Automatic Eye Fundus Image Processing

For more than 10 years, I have been managing research about the processing of eye fundus images, applied to Diabetic Retinopathy. This pathology is the main reason for defective eyesight and blindness for under 55-year old people, in industrial countries. The target of this research is the automatic detection of Diabetic Retinopathy at its early stages, and the automatic diagnosis and monitoring of this disease.
This is obtained by automatic detection and quantization of microaneurysms, haemorrhages and exudates. 
Our research and publications on this matter are available on the following websites, which are both those of my PhD students:

 Frédéric Zana’s personal page dealing with the processing of angiographic images

Thomas Walter’s personal page dealing with more recent research about eye fundus color images


General Hardware architectures

My group has designed numerous processors to implement the algorithms proposed by the Mathematical Morphology. For example:

 

 

 

ASIC PIMM1
40 000 gates - 1.5 µm

 

FPGA-based
Processor Board

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Multimedia Hardware Architectures

This group is involved in different multimedia projects whose goals are to design parallel hardware architectures to allow real-time image segmentation in the framework of MPEG4 applications. For example:

  • Momusys European program. In this program, the objective is to propose an efficient parallelized implementation of the Mathematical Morphological operators into DSP
  • M4M (MPEG FO(U)R MOBILES) which is part of the Medea European program. In this project, we will participate to the design of ASICs which will be dedicated to MPEG4 applications

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Continuous blood glucose monitoring system

Three laboratories are working on this project :

  • Pr. G. Wilson, University of Kansas, Department of Chemistry, Lawrence, KS 66045, USA
  • Pr. G. Reach, INSERM U.341, Paris, France
  • Dr. J-C. Klein, ENSMP CMM, Paris, France

The goal is to design a miniaturized system able to continuously display the blood glucose level and to trigger an alarm in case of hypoglycemia. This would be a major help for diabetic patients.

The system is composed of a :

  • Miniaturized bio-chemical sensor : diameter = 0.3 mm
  • Electronic Control Unit (ECU) in charge of processing the data provided by the sensor, of storing and displaying the blood glucose value. The ECU can also be used to transfer the stored data to a personal computer

Electronic Control Unit

Sensor implanted in the user's forearm

The Electronic Control Unit is connected by wire to the sensor

This program is currently funded by :

  • The NIH : DK30718-11
  • National Applied Science, Portland, Oregon U.S.A.

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Address

Ecole des Mines de Paris
Centre de Morphologie Mathematique
35, rue St-Honoré
77305 Fontainebleau
FRANCE

E-mail : klein@cmm.ensmp.fr

Phone : +33 1 64 69 47 06
Fax : +33 1 64 69 47 07

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Last modification : 28/03/2006